A combined supplement of calcium and vitamin B6 might help curb symptoms of premenstrual syndrome (PMS), state researchers at Hamadan University of Medical Sciences in Iran. In this double-blind, randomized, controlled study, 76 female college students were divided into two groups, with one group receiving daily 500 milligrams of calcium and 40 milligrams of vitamin B6, and the second group receiving only the vitamin B6 twice daily for two months. PMS symptoms were assessed by the Beck Depression Inventory and daily symptom records. Results showed that both groups showed improvements in symptoms, but the combination of calcium and vitamin B6 was significantly more effective.
Masoumi S, Ataollahi M, Oshvandi K: Effect of combined use of calcium and vitamin B6 on premenstrual syndrome symptoms. Journal of Caring Sciences 2016; 5:67-73.