Vitamin E might be just what the neurologist ordered, if the results of a study from the University of Technology Mara in Malaysia prove true. More than 120 volunteers between 35-years-old and older who had cardiovascular risk factors and MRI-confirmed lesions in the white matter of their brains were randomized to receive either 200 milligrams of mixed tocotrienols (a form of vitamin E) or placebos twice daily for two years. Lesions were measured from MRI images taken at baseline, 1 year, and 2 years. Results showed that after 2 years, the average white matter lesion volume had decreased significantly in the supplemented group, but not in the placebo group.
In Perspective: White matter lesions are signs of cerebral small vessel disease and reflect degeneration of nerves and other tissue damage.
Gopalan Y, Shuaib I Magosso E, et al: Clinical investigation of the protective effects of palm vitamin E tocotrienols on brain white matter. Stroke 2014;45:1422-1428.