A supplement rich in flavonoids and fish oil reduced inflammation and improved immune function in obese subjects, in a study from Case Western Reserve University in Cleveland. About 50 overweight or obese women between the ages of 40- and 70-years-old were given either placebos or a mixed flavonoid-fish oil supplement containing:
1000 milligrams quercetin,
400 milligrams isoquercetin,
120 milligrams epigallocatechin or EGCG from green tea extract,
400 milligrams omega-3s as 220 milligrams EPA and 180 milligrams DHA from fish oil,
1000 milligrams vitamin C,
40 milligrams niacinamide, and
800 micrograms folic acid.
Fasting blood samples were taken at the start of the study and at week 10. Results showed that blood levels of all the compounds in the supplement increased and at the same time there was an improvement in immune function and a reduction in markers for chronic inflammation.
Cialdella-Kam L, Nieman D, Knab A, e al: A mixed flavonoid-fish oil supplement induces immune-enhancing and anti-inflammatory transcriptomic changes in adult obese and overweight women. Nutrients 2016; May 11th.