Optimal iron and zinc intake might be necessary for mood, mind, and memory in pre-menopausal women. Researchers at Deaken University in Melbourne, Australia reviewed the research on intake of these minerals from ten randomized controlled trials and one non-randomized trial. Results showed that seven studies found improvements in mood and cognition after iron supplementation. Women taking iron supplements showed improved memory and intellectual ability. Zinc supplementation, both as an adjunct to traditional antidepressant therapy and as a therapy on its own, improved symptoms of depression in three trials. Improving zinc status also appeared to enhance cognitive and emotional functioning, according to the researchers.
Lomagno K, Hu F, Riddell L, et al: Increasing iron and zinc in pre-menopausal women and its effects on mood and cognition. Nutrients 2014;6:5117-5141.z