Low vitamin D levels could increase the risk for early death, according to a study from Copenhagen University Hospital in Denmark. All-cause mortality and cause-specific mortality were compared in a group of 95,766 people genotyped for factors that affected vitamin D status. The subjects were followed for 5.8 to 19.1 years, during which time more than 10,000 of them died. Results showed that genetically low vitamin D levels were linked with early death from any cause, including cancer, but not to heart-related events. This was clear even when other factors, such as smoking, drinking alcohol, physical activity levels, blood pressure, cholesterol levels, and body mass index (BMI) were taken into account.
Afzal S, Brondum-Jacobsen P, Bojesen S, et al: Genetically low vitamin D concentrations and increased mortality. British Medical Journal 2014;November 18th.