Researchers at Victoria University in Melbourne, Australia report that low intake of certain vitamins, especially the B vitamins, increases the risk for depression. The B vitamins are required for proper functioning of the methylation cycle, monoamine oxidase production, DNA synthesis, and the repair and maintenance of phospholipids in cell membranes. For example, vitamin B6 is important in the conversion of the amino acid tryptophan to the neurotransmitter serotonin. Vitamin B12 is important in maintaining the integrity of the myelin sheath around each neuron’s axon, allowing neurons to communicate efficiently and effectively. A deficiency of vitamins B1, B6, B12, or niacin could influence memory function, cognitive impairment, and even dementia risk.
Elizabeth Somer, M.A.,R.D.
Mikkelsen K, Stojanovska L, Apostolopoulos V: The effects of vitamin B in depression. Current Medicinal Chemistry 2016; September 20th.