A pregnant woman can significantly reduce her chances of developing pre-eclampsia and having a small for gestational age baby if she supplements with folic acid, state researchers at Korea University College of Medicine in Seoul. Folic acid supplementation and favorable maternal and fetal outcomes were studied in 215 pregnant women. Results showed that blood folic acid levels in women who supplemented were more than double that of women who did not supplement, while homocysteine levels decreased. The incidence of pre-eclampsia was much lower in the supplemented women compared to the unsupplemented women, as were the odds of having a small for gestational age baby (9.2% compared to 20%, respectively).
Kim M, Ahn K, Ryu K, et al: Preventive effects of folic acid supplementation on adverse maternal and fetal outcomes. PLoS One 2014;9:e97273.